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SKU: 71520113509
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Description

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated mA-demethylation of NANOG mRNA

This was paralleled by changes in certain intracellular signaling proteins, including Akt, which is commonly linked with survival and growth-related pathways

The marked metabolites identified in this study aligned with energy metabolic pathways, including carbohydrate metabolism (glycolysis/gluconeogenesis and glyoxylate, dicarboxylate metabolism, and pyruvate metabolism), propanoate metabolism, and methane metabolism (Fig