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Removes dirt and impurities effectively

Sugimoto T, Watanabe K, Yoshida S, Aino M, Furiki M, Shiono M, Matoh T, Biggs AR

In vivo results from the DMM-induced OA mouse model further confirmed that Ce@D&P NPs significantly alleviated cartilage damage, reduced osteophyte formation, and regulated lipid metabolism-related markers through intra-articular injection

To overcome this drawback, the invention provides methods for identifying those vectors in a genetic vaccine population that exhibit not only the desired tissue localization and longevity of DNA integrity in vivo, but retention of maximal antigen expression (or expression of other genes such as cytokines, chemokines, cell surface accessory molecules, MHC, and the like)