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While early research is promising, it is still an experimental compound with limited human data

As we age, natural GHK levels in the body decline, from around 200 ng/mL in the plasma of a 20-year-old to roughly 60 ng/mL by age 60

Therefore, while existing evidence supports low local toxicity, comprehensive in vitro and in vivo immunogenicity testing remains advisable prior to clinical translation [71, 191]

Ultimately, 706 participants met the eligibility criteria and were randomly assigned to one of several treatment arms: once-weekly subcutaneous injections of Cagrilintide at doses of 0.3, 0.6, 1.2, 2.4, or 4.5 mg, once-daily liraglutide 3.0 mg, or a volume-matched placebo