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(2024) SARS-CoV-2 virulence factor ORF3a blocks lysosome function by modulating TBC1D5-dependent Rab7 GTPase cycle

Moreover, MDSC-specific TIPE2 knockout significantly improved anti-tumor immune responses, further underscoring its potential as a therapeutic target [141]

Subsequently, 30 l of purified NCOA4 protein (as described above), pre-adjusted to pH 4.5 by mixing with 150 l of 10 mM sodium acetate buffer (pH 4.5), was immobilized at a flow rate of 10 l min 1 for 5 min over three cycles