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For instance, spherical nucleic acid (SNA used to dysregulate miRNA, i.e., miR92b target of RNA interference) encapsulated liposomal nanoparticles conjugated with brain targeting peptides, i.e., rabies virus glycoprotein (RVG, is a neurotropic viral peptide targeting nicotinic acetylcholine receptors expressed on the BCECs, neurons, and glioma cells) and apolipoprotein-E

The challenges in assessing the efficacy of drugs are compounded by the need for careful patient selection and clinical stratification

doi: 10.1016/j.rehab.2016.02.001 196 PedrosoJLValeTCBraga-NetoPDutraLAFranaMCJr.TeiveHAGet al

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