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When two or more independent drugs are combined, their effects add up, and the Bliss synergy score is 0 (39)

Elevated AGE-modified ApoB in sera of euglycemic, normolipidemic patients with atherosclerosis: relationship to tissue AGEs

How and why do T cells and their derived cytokines affect the injured and healthy brain

However, translating these findings faces challenges, including a narrow therapeutic window, patient heterogeneity, and the need to balance efficacy with safety concerning systemic iron and lipid metabolism