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(16)Gly-Glu(otBu)-Pro-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val- (16) Preparation of Gly-Glu(otBu)-Pro-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-resin (15)Fmoc-Gly-Glu(otBu)-Pro-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-1050530105010603DMF3DMF220.53 Gly-Glu(otBu)-Pro-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val- In step (15) Fmoc-Gly-Glu(otBu)-Pro-Pro-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val- Add decapping reagent to the resin, react at 10-50C for 5-30 minutes, drain with a vacuum pump, re-add capping reagent at 10-50C, react for 10-60 minutes, drain, wash with isopropanol for 3 times, DMF for 3 times , washed twice with DMF and twice with methanol, soaked in methanol for 0.5 to 3 hours, drained, and dried with nitrogen to form very dry particles

Tendon and ligament repair, gastrointestinal mucosal healing, soft tissue recovery, and neuroprotective signaling are all supported by reproducible rodent and in vitro work, while the human evidence remains limited to one unpublished Phase 2 IBD trial and a small number of preliminary studies

References to research reflect published literature and do not constitute an endorsement of any specific therapeutic use

in males, its pro-erectile effect is secondary to central mechanisms stimulating nitric oxide production in penile tissue [3]