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Many arginine-methylated proteins have been shown to interact with DNA or RNA, and the arginine residue acts as an important hydrogen donor for the phosphate backbone

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On examination, the findings may include clinical features of fever or hypothermia, tachycardia, tachypnea, dullness to chest percussion in the areas of consolidation, pleural rub, hypotension, altered sensorium, or delirium.[] It is important to remember that the clinical presentation may have some overlap with other medical emergencies reported to be associated with the use of psychotropics

This creates a potentially synergistic relationship