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Unlike homeostatic IEC shedding where barrier integrity is maintained by rapid basolateral tight-junction protein redistribution and zipper-like replacement by neighboring cells (246, 247), necroptosis, in which several nearby IECs lose contact, has been documented to accompany TNF--induced shedding (243, 248)

Similarly, in ex situ organ perfusion (ESOP) (60), the absence of the biological role of organs, such as the liver, leads to the inability to scavenge oxygen radicals generated by oxidative stress, thus making such a technique more challenging compared with physiological conditions ( 4.3 Endogenous and exogenous coagulation systems Under normal physiological conditions, coagulation mechanisms include both coagulation and anticoagulation, and the dynamic balance between them plays a key role in maintaining normal blood flow and preventing coagulation (61)

Alpha Lipoic Acid plays the role of antioxidants and Pycnogenol as fighting inflammation and preventing damage of skin by the environment

Through the vagina and cervix, a hysteroscope allows surgeons to remove or destroy fibroids without abdominal incisions, making them ideal for smaller, accessible fibroids and usually requiring only a short recovery